Prevalence of Mantoux test positivity among apparently healthy children in Maiduguri, Nigeria.
Method: The study was descriptive and cross-sectional, conducted in Maiduguri, Nigeria, among apparently healthy 3-59 months old children who attended the child welfare clinics of the University of Maiduguri Teaching Hospital and two Primary Health Care centres from May to August 2008. All children who fulfilled the inclusion criteria were evaluated for history of BCG vaccination and Mantoux tested.
Results: The study included 390 children, comprising 201 (51.5%) males and 189(48.5%) females; the male to female ratio was 1.1:1. Thirty one out of the 390 (7.9%) children had a positive Mantoux reaction, 27(87 %) of whom had induration of 10-14mm, while the remaining 4 (13 %) had induration of 15-20mm. The prevalence of Mantoux positivity among the vaccinated children was 10.1% and among the non-vaccinated children was1.1%, (p= 0.0034). No significant statistical difference for Mantoux positivity was observed between the sexes, (p= 0.087), and the different age groups, (p= 0.159).
Conclusion: Although, positive Mantoux response is usually attributed to TB infection, the effect of previous BCG on Mantoux test reactivity especially in children should be taken into consideration in the interpretation of Mantoux test responses.
Modu Gofama Mustapha, Department of Paediatrics, UMTH, Maiduguri, Nigeria
Ashir Mohammed Garba, Department of Paediatrics, UMTH, Maiduguri, Nigeria
Adamu Ibrahim Rabasa, Department of Paediatrics, UMTH, Maiduguri, Nigeria
Mohammed Suleman Gimba, Department of Paediatrics, UMTH, Maiduguri, Nigeria
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Date published: 2009-11-09
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